Bioavailability is the scientific term for how much of a nutrient is actually absorbed, delivered into the bloodstream, and used by your body.
A supplement may contain a high dose — but if it’s poorly absorbed, you’re not getting the benefit.
💡 Example:
Standard turmeric extract? Often <1% absorbed.
Curcumin delivered with micelles, fat, and polyphenols? Up to 185x more bioavailable
Why bioavailability matters:
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You get real results with less strain on digestion
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You avoid “expensive urine” syndrome (passing nutrients unabsorbed)
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You reduce the need for megadosing, which can cause imbalances
Most synthetic capsules are designed for shelf life — not absorption.
MILESTONE® formulations are designed to deliver real nutrients, in real food-based systems, that the body can recognize and use.
In whole foods, nutrients rarely show up alone — and they never work in isolation.
Let’s take a few real examples of nutrient synergy:
- Vitamin C is more potent in citrus when paired with bioflavonoids
- Iron in plant foods is better absorbed with natural vitamin C and enzymes
- Vitamin D, A, and K need dietary fat for optimal transport
- Polyphenols work in tandem with fiber and trace minerals to improve gut regulation
This is what scientists call the food matrix effect:
Nutrients change behavior depending on what else surrounds them.
A whole food supplement designed to mimic this natural synergy will always deliver more impact than a product with a single synthetic isolate.
At MILESTONE®, this principle drives every formulation — from fermented pomegranate to high phenolic olive oil to algae-based D3 in its native fat carrier.
We don’t stack “hero ingredients.” We recreate how food talks to your body.
Not all supplements are created equal — and not all forms of nutrients make it through digestion, into your cells, and into action.
Here’s what actually improves nutrient absorption and bioavailability:
Fats
Fat-soluble vitamins like D, A, K, and E require dietary fats — especially monounsaturated fats like olive oil — for transport and uptake.
→ Vitamin D absorption with olive oil is significantly higher than in powder or tablet form
Polyphenols
These plant-based compounds aren’t just antioxidants — they act as cellular messengers that enhance absorption of co-nutrients and improve gut permeability.
→ They also protect sensitive nutrients from degradation during digestion.
Fermentation
Fermentation pre-digests certain compounds, increasing the bioaccessibility of B12, iron, and polyphenols — and creating new postbiotic compounds like urolithins, which support mitochondrial health.
Micellization
This is a smart delivery method that mimics the body’s own fat-emulsifying system. It dramatically enhances fat-soluble nutrient absorption, especially for notoriously hard-to-absorb compounds like curcumin.
Matrix Synergy
Whole food supplements preserve the original nutrient environment — fibers, enzymes, lipids — that activate and support nutrient function in the body. This is why MILESTONE® designs around natural supplement absorption, not artificial bioenhancers.
In short, the best high absorption supplements use the body’s language:
Food. Fermentation. Fats. Synergy.
Let’s take Vitamin C as an example.
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🍊 In an orange, it comes with flavonoids, enzymes, sugars, acids, and fiber — all working together to enhance its uptake and antioxidant behavior.
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💊 In an isolated capsule, it’s a lone molecule — often oxidized by the time it reaches the gut, and without the cofactors that make it functional.
This is the bioavailability gap: the difference between what’s in the supplement… and what your body can actually use.
🧠 Clinical studies show that nutrients in whole food or food-mimicking environments are absorbed faster, retained longer, and used more efficiently by cells.
So it’s not just about what is in the capsule — it’s about how your body receives it.
That’s what separates natural supplement absorption from the empty promises of synthetic megadosing.
You could take two supplements with the same ingredients — and get radically different results. Why? Because form = function.
Let’s break it down:
Dry Capsules & Tablets
- Often contain binders or heat-processed ingredients
- Delay breakdown in the gut
- Poor carriers for fat-soluble nutrients like D3 or curcumin
- Risk of malabsorption in people with low stomach acid or inflammation
Liquids & Emulsions
- Begin absorption in the mouth (sublingual entry)
- Bypass poor stomach conditions
- Ideal for fast delivery and fragile nutrients
- Can be combined with oils or micelles for maximum absorption
Food Matrix-Based Formats (like MILESTONE®)
- Nutrients delivered in their natural environment (fats, fiber, polyphenols)
- Better tolerated by sensitive systems
- Mimic how your body evolved to absorb food, not pills
- Perfect for high absorption supplements designed around real-world biology
That’s why MILESTONE® uses:
- Fermented bases
- High phenolic olive oil as a fat and antioxidant carrier
- Micellized curcumin + pomegranate blends
- Liquid algae-based D3 in olive oil
→ Because absorption starts with form — and function starts with food.
Let’s explore how different nutrients in our line were engineered for absorption — not just label appeal. Aiming for the highest standard of high absorption food-based supplements.
Micellized Curcumin + Fermented Pomegranate
Standard curcumin is famous for being poorly absorbed. But when delivered in micelles — fat-emulsifying structures — its bioavailability increases up to 185x.
Our formula doesn’t stop there — it adds:
- Fermented pomegranate concentrate, which supports gut function and promotes urolithin A generation
- Plant-based Vitamin D3 for immune modulation
- Liquid format to ensure immediate uptake and minimal digestive strain
This isn’t a capsule with three ingredients.
It’s a high absorption supplement designed to work with your biology, not bypass it.
Vitamin D3 + High Phenolic Olive Oil
Our algae-based D3 is:
- Vegan
- Clean-sourced
- Delivered in cold-extracted, polyphenol-rich olive oil
This combination does two things:
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Enhances vitamin D absorption by providing the exact fat medium D3 needs to enter the bloodstream
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Adds olive polyphenols like hydroxytyrosol, which support anti-inflammatory balance and cellular protection
Iron + Potassium + Polyphenol Matrix
Many iron supplements cause digestive distress or constipation — because they’re delivered in an unnatural, unbuffered form.
MILESTONE® addresses this by pairing:
- Iron with fermented pomegranate, which provides vitamin C, tannins, and organic acids that enhance iron uptake
- Potassium to support electrolyte and gut balance
- Polyphenols to modulate inflammation and assist red blood cell formation
Formulation matters. And synergy isn’t optional — it’s biological.
At MILESTONE®, we simply ask:
“What actually works in the body — and how do we deliver it that way?”
Our approach to natural supplements absorption includes:
✅ Bioavailable Nutrients
→ We select forms already used by the body: methylated B12, micellized curcumin, algae-based D3
✅ Synergistic Delivery Systems
→ Like olive oil, fermented fruit matrices, polyphenol blends, and ionic minerals
✅ Liquid and Matrix Formats
→ Because powders and pills miss key stages of digestion, especially for sensitive users
✅ Fermentation + Food-First Logic
→ We include pre-digested forms that increase nutrient retention, gut function, and mitochondrial support
We don’t use megadoses to compensate for poor delivery.
We use smart design to mimic nature’s blueprint.
That’s what makes our formulas feel different — and work better. A true champion in naturally high absorption supplements.