therapeutic vs daily use functional foods

What Does High-Phenolic Really Mean?

What does high-phenolic mean? The term refers to olive oils that contain elevated levels of naturally occurring polyphenols — bioactive compounds responsible for antioxidant, anti-inflammatory, and cellular defense benefits. According to the European Food Safety Authority (EFSA), oils with >250 mg/kg of hydroxytyrosol and related compounds may claim to protect blood lipids from oxidative stress 1.

At MILESTONE®, our oils exceed this threshold dramatically — reaching over 1,000 mg/kg of total phenolics, validated via HPLC and Folin–Ciocalteu analysis 2.

Types Of Polyphenols That Define 'High-Phenolic'

  • Oleocanthal: Gives the peppery bite — acts like ibuprofen by inhibiting COX-1 and COX-2 enzymes
  • Oleacein: Bitter and astringent — powerful antioxidant and NF-κB inhibitor
  • Hydroxytyrosol & tyrosol: Found in free and bound form — protect LDL from oxidation

So when we ask what does high-phenolic mean, we’re really asking: how much of these powerful molecules are present — and preserved?

Why It Matters — Potency Equals Function

  • MILESTONE® olive oils offer pharmaceutical-grade phenolic density — up to 10x more than standard extra virgin oils
  • They are analyzed under controlled, cold-pressed, and unfiltered conditions to preserve compound integrity
  • High-phenolic oils act on gene expression (e.g., SIRT1, PPARγ), reduce oxidative stress, and modulate inflammation

True high-phenolic olive oil is not just extra virgin — it’s clinically potent and functionally verified 3.

Summary: High-Phenolic Means Therapeutic By Nature

If you’ve ever asked what does high-phenolic mean, the answer is simple: a food that crosses into therapeutic territory. Clinically meaningful, analytically tested, and rich in natural defense compounds.

Tip: High-phenolic oils should list polyphenol content (mg/kg) and analytical method. If it’s not tested, it’s not therapeutic.

  1. EFSA Panel, EFSA J, 2011[]
  2. Karkoula et al., J Agric Food Chem, 2012); (Cicerale et al., Molecules, 2012); (Fito et al., Br J Nutr, 2007[]
  3. Covas et al., Ann Intern Med, 2006); (Agrawal et al., Curr Pharm Des, 2010); (Schwingshackl & Hoffmann, PLoS One, 2014[]
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