Urolithins are gut-derived metabolites formed after consuming pomegranate ellagitannins. They play a vital role in reducing inflammation, supporting gut health, and improving cellular energy — particularly urolithin A, which is now being studied for its mitochondrial and anti-aging effects.

When ellagitannins from pomegranate are metabolized by gut bacteria into urolithins, they can:

• Promote mitophagy — the recycling of damaged mitochondria
• Support energy production and muscular endurance
• Reduce systemic inflammation and oxidative stress
• Strengthen gut barrier integrity and microbiota balance

👉 Our fermented pomegranate formula is crafted to support urolithin production naturally by enhancing gut bioavailability.

Recent research is uncovering the therapeutic power of urolithins:

• Urolithin A activates mitophagy, enhancing muscle function and energy metabolism in both preclinical and human trials ¹.
• Ellagitannins from pomegranate are converted to urolithins by gut microbiota, but conversion depends on the individual’s microbial profile ².
• Fermentation may improve the bioaccessibility of ellagitannins, enhancing urolithin formation ³.

These findings position urolithins as a next-generation target in food-based therapeutics.

Urolithins are the reason why pomegranate is more than just a fruit — it’s a biological activator. By supporting mitochondrial function, gut health, and anti-inflammatory responses, these metabolites offer truly functional benefits for long-term vitality.

⚠️ Since not everyone produces urolithins equally, choosing fermented and polyphenol-rich pomegranate products may support optimal conversion and benefit.